Table 2.

Psychiatric Characteristics and Trauma History

				Univariate Model		Multivariate Model
		Cases	Controls	OR (95% CI)	p-value	OR (95% CI)	p-value
Major Depressive Disorder
	EPDS score	14 (12 – 17)	2 (0 – 4)
	First depressive episode, %	46.8	0.0
	Previous MDD, %	53.2	14.8	6.54 (5.13 – 8.37)	7.94E-56	6.28 (4.86 – 8.13)	3.82E-48
	Previous PPD, %	24.9	5.8	5.34 (3.84 – 7.49)	2.03E-25	5.39 (3.80 – 7.73)	7.67E-23
	Family History PPD, %	15.9	4.7	3.79 (2.61 – 5.58)	1.08E-12	3.74 (2.54 – 5.59)	1.56E-11
Anxiety Disorders, %
	Lifetime anxiety, any	47.2	7.1	11.64 (8.67 – 15.83)	3.52E-71	11.13 (8.11 – 15.48)	2.03E-59
	GAD	13.9	2.5	6.32 (4.00 – 10.33)	4.16E-17	5.86 (3.59 – 9.95)	9.20E-14
	Panic Disorder	17.6	2.4	8.61 (5.48 – 14.07)	5.81E-25	8.13 (5.00 – 13.82)	1.94E-20
	OCD	22.1	1.0	27.04 (14.78 – 55.52)	1.09E-45	22.33 (12.12 – 46.08)	5.32E-37
	PTSD	9.0	1.3	7.76 (4.23 – 15.42)	6.26E-13	6.88 (3.62 – 14.19)	2.50E-10
Suicidality, Past Month		35.9	1.9	29.34 (18.33 – 49.92)	7.29E-76	26.15 (16.23 – 44.72)	2.78E-65
Abuse/Trauma Summary Score, median (IQR)		2 (1 – 4)	1 (0 – 2)	1.37 (1.30 – 1.45)	4.30E-31	1.36 (1.29 – 1.45)	1.39E-27
Number of events, %
	0	20.5	40.4
	1	14.6	21.3	1.35 (0.95 – 1.93)	0.09	1.32 (0.90 – 1.90)	0.15
	2+	64.9	38.4	3.34 (2.55 – 4.39)	9.30E-20	3.30 (2.49 – 4.39)	9.90E-18
Child sexual abuse		27.4	13.3	2.46 (1.86 – 3.25)	2.51E-10	2.51 (1.87 – 3.37)	9.18E-10
Adult sexual abuse		23.6	9.1	3.07 (2.25 – 4.19)	9.17E-13	2.87 (2.07 – 3.97)	1.90E-10
Upsetting memories of giving birth		21.5	7.7	3.49 (2.56 – 4.80)	1.38E-15	3.70 (2.66 – 5.16)	2.00E-15
Child having life-threatening illness or death		9.2	7.7	1.21 (0.81 – 1.80)	0.34	1.25 (0.82 – 1.91)	0.30