Table 2.

Relative potency and maximum inhibition of acute DM exposure on SCO parameters at different DIVs.

DIVs	SCO frequency		SCO amplitude
	${\text{IC}}_{50}$ (nM) (95% CI)	Max. inhib. (%) (95% CI)	${\text{IC}}_{50}$ (nM) (95% CI)	Max. inhib. (%) (95% CI)
6	139.6 (73.0, 262.9)	100.0 (82.9, 124.7)	37.6 (22.5, 62.3)	100.0 (88.6, 112.7)
8	190.8 (126.4; 1,471.0)	90.9 (73.6, 206.8)	21.3 (13.6, 33.4)	88.2 (80.0, 97.2)
10	N.D.	$29.5\pm 3.7$a	29.8 (20.3, 43.5)	67.8 (61.9, 74.1)
12	N.D.	$13.6\pm 10.4$a	78.1 (26.2, 222.2)	60.5 (43.8, 85.5)

Note: The half-maximal inhibitory concentration (${\text{IC}}_{50}$) values and maximum inhibition were obtained by fitting the data in Figure 3B with a nonlinear logistic equation using Prism GraphPad software. CI, confidence interval; DIV, days in vitro; DM, deltamethrin; Max. inhib., maximal inhibition; SCO, spontaneous ${\mathrm{Ca}}^{2+}$ oscillations; N.D., not determined.

^aSince the data obtained from 10 and 12 DIV did not permit curve fitting, the maximal inhibition was reported at $1\mathrm{\mu }\mathrm{M}$ DM.