Figure 2.

Natural cubic splines with 2 degrees of freedom (solid line) and associated 95% confidence intervals (dashed lines) illustrating the associations between relative telomere length (T:S) and exposures to ${\mathrm{PM}}_{2.5}$ and black carbon (${\mathrm{\mu }\mathrm{g}/\mathrm{m}}^3$) among rural Chinese women using household biomass stoves. Mean change is relative to the mean exposure (vertical black line). Results presented as univariate (top); multivariable models adjusted for age, waist circumference, socioeconomic status, exposure to environmental tobacco smoke, dietary sodium intake, physical activity, and the time of day and day of the week of DNA collection (middle); and ambient temperature (bottom). The vertical cyan lines along the x-axes show the distribution of the pollutant exposures. ${\mathrm{PM}}_{2.5}$, particulate matter $\le 2.5\mathrm{\mu }\mathrm{m}$ in aerodynamic diameter; T:S, telomere repeat sequence copy number to single-copy gene ratio.