Table 2.
Prolactin serum levels, anthropometric and biochemical variables in patients with type 2 diabetes mellitus compared with control
| Parameters | Control | T2DM | 95% CI | P |
|---|---|---|---|---|
| n (%) | 25 (23.80) | 80 (76.19) | 30.3640-67.1773 | 0.001* |
| BMI (kg/m2) | 25.30±1.55 | 31.05±1.66 | 5.0070-6.4930 | 0.001* |
| SBP (mmHg) | 123.65±6.78 | 148.82±11.92 | 20.1985-30.1415 | 0.001* |
| DBP (mmHg) | 79.44±6.84 | 90.57±8.97 | 10.1665-20.1415 | 0.001* |
| FBG (mg/dl) | 81.77±8.83 | 141.65±22.72 | 50.6290-69.1310 | 0.001* |
| HbA1c | 5.77±1.71 | 8.54±1.51 | 2.0616-3.47784 | 0.001* |
| Fasting insulin (mIU/l) | 8.64±2.55 | 17.49±4.19 | 7.0912-10.6088 | 0.001* |
| HOMA-IR | 1.09±0.11 | 6.11±2.39 | 4.0685-5.9715 | 0.001* |
| HOMA-β (%) | 125.90±6.89 | 80.05±6.62 | −48.8873-42.8127 | 0.001* |
| TG (mg/dl) | 112.89±9.62 | 185.44±11.45 | 67.5283-77.5717 | 0.001* |
| TC (mg/dl) | 129.11±11.80 | 196.52±12.62 | 61.7598-73.0602 | 0.001* |
| LDL (mg/dl) | 49.80±5.61 | 118.4±12.92 | 63.3130-73.8870 | 0.001* |
| HDL (mg/dl) | 56.73±3.63 | 41.58±8.61 | −18.6679-11.6321 | 0.001* |
| VLDL (mg/dl) | 22.60±4.89 | 37.08±4.31 | 12.4570-16.5030 | 0.001* |
| AI | 0.06±0.001 | 0.289±0.03 | 0.2171-0.2409 | 0.001* |
| CRP (mg/L) | 1.21±0.72 | 2.9±1.51 | 1.0687-2.3113 | 0.001* |
| Prolactin (ng/ml) | 10.66±2.45 | 36.84±6.29 | 23.6197-28.7403 | 0.001* |
*P<0.01. BMI: Body mass index, SBP: Systolic blood pressure, DBP: Diastolic blood pressure, FBG: Fasting blood glucose, HbA1c: Glycated hemoglobin, HOMA-IR: Homeostatic model assessment-insulin resistance, β%: β-cell function, S%: Insulin sensitivity, TG: Triglyceride, TC: Total cholesterol, LDL: Low-density lipoprotein, HDL: High-density lipoprotein, VLDL: Very low-density lipoprotein, AI: Atherogenic index, CRP: C-reactive protein, T2DM: Type 2 diabetes mellitus, SD: Standard deviation