Table 1.

Sequencing technology characteristics. (Read number per dollar is hard to establish considering different pricing structures and instrument costs. Here, we assume a laboratory would use sequencing cores for Illumina and PacBio sequencing while performing ONT MinION sequencing themselves.)

technology	read number/$1 k	read accuracy (%)	consensus accuracy
Illumina NextSeq	∼2 × 108	99.9	N/A
Pacific Biosciences (PacBio) sequel	∼4 × 105	89	>99%
Oxford Nanopore Technologies (ONT) MinION	∼5 × 106	88	>97.5%a

^aConsensus accuracy using our R2C2 approach as published [9,10].