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. 2019 Oct 7;374(1786):20190088. doi: 10.1098/rstb.2019.0088

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© 2019 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 5. — POU phylogenetic tree. (a) ML inference of Homeobox domain using LIM homeobox as an outgroup. LIM domains were downloaded from (http://homeodb.zoo.ox.ac.uk/download.get). Pou domains were selected from a wide range of metazoans available in our dataset, plus the choanoflagellate sequence (marked in red). Supports are SH-like approximate likelihood ratio test (left) and UFBS, respectively (right) calculated with IQ-TREE v. 1.5.1. (b) Maximum-likelihood inference of Pou transcription factors using the whole protein, the Pou domain and the Homebox domain. M. fluctuans Pou sequence falls within POU-2 group (marked in red).