Table 2.
The relationships between HIF‐1α expression in the myeloid tissues of MDS patients and blood‐related clinicopathologic parameters
| Blood‐related parameters | Median value (range) | T value | P value | |
|---|---|---|---|---|
| HIF‐1α (−) | HIF‐1α (+) | |||
| Initial cells (%) | 0.50 (0.00‐13.20) | 5.00 (0.00‐18.50) | −1.16 | .25 |
| Leukocytes (×109/L) | 2.40 (1.52‐3.30) | 3.06 (0.98‐10.53) | −3.57 | <.001*** |
| Hemoglobin (g/L) | 64.00 (40.30‐108.00) | 67.00 (26.30‐113.40) | 0.18 | .86 |
| Platelets (×109/L) | 22.50 (2.00‐387.00) | 73.30 (4.30‐477.80) | −0.85 | .40 |
| Neutrocytes (×109/L) | 1.20 (0.70‐2.10) | 1.49 (0.08‐8.70) | −2.25 | <.05* |
| Lactate dehydrogenase (μ/L) | 174.00 (9.00‐732.00) | 242.00 (105.00‐2777.00) | −0.24 | .81 |
| Microglobulin (μg/L) | 3.55 (2.12‐6.54) | 3.20 (1.42‐6.33) | 1.19 | .24 |
Abbreviations: HIF‐1α, hypoxia‐inducible factor 1 alpha; MDS, myelodysplastic syndrome.
*
P < .05.
***
P < .001.