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. 1998 Jan 15;18(2):687–697. doi: 10.1523/JNEUROSCI.18-02-00687.1998

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Fig. 8. — Ischemia-induced protein tyrosine nitration is reduced in MnSOD Tg mice. Bright-field micrographs of nitrotyrosine immunoreactivity in coronal brain sections from mice killed 24 hr after sham surgery (A, wild-type; C, MnSOD Tg) or after MCA occlusion ischemia (B, wild-type;D, MnSOD Tg). Note the great increase in nitrotyrosine immunoreactivity in the injured cortex of the wild-type mouse (B, arrow) relative to the MnSOD Tg mouse that showed less of an increase in nitrotyrosine immunoreactivity (D, arrow). Similar differences were observed in each of four wild-type and four MnSOD Tg mice examined.