Fig. 2.
Pharmacologically induced changes in SCN microdialysate 5-HT concentrations. Top, Middle, Effects of localized perfusions with ACSF solutions containing high [K+] or no Ca2+, respectively, on 5-HT output. Solid bars denote the 2 hr duration of the treatments. Bottom, Effect of intraperitoneal injection of 8-OH-DPAT on 5-HT output. Arrow designates the time of injection. The sample interval was 20 min for all treatments; n = 4–5 for each experiment; *p < 0.05 compared with pretreatment levels.