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Time of day difference in the effect of novel wheel running on 5-HT release averaged over the entire 3 hr running period from the SCN region. The vertical position and length of thesolid bars denote the mean level of 5-HT release and period of wheel running, respectively. Data from all animals in each group are included irrespective of running intensity. Solid bar at the top denotes the dark phase. Groups with different letters are different from each other;p < 0.05.
