Fig. 5.
Effects of 1 mm 4-AP and 6 mm TEA on current-clamp recordings from hair cells in the semi-intact epithelial preparation. A, Voltage oscillations recorded in normal extracellular solution (control, solid line: Istim = 225 pA;f = 82 Hz; Vrest = −70 mV) were eliminated by 4-AP and partially restored when 4-AP was removed (recovery, dotted line). B, TEA transformed the damped sinusoidal oscillations found in this cell (control, solid line: Istim = 200 pA; f = 67 Hz; Vrest= −94 mV) into spike-like oscillations. This effect was partially reversed when TEA was removed (recovery, dotted line). Recordings from both cells were made using perforated patch. The traces in A are the average of five presentations.