Table 2.

Tissue content of monoamines and their metabolites in striatum from the B6 congenic strain of D2 receptor mutant mice

Genotype	n	DA	DOPAC	HVA	NE	5-HT	5-HIAA
−/−	12	5688  ± 715	1441  ± 139	1989  ± 148	265  ± 36	333  ± 26	400  ± 33
+/−	29	5997  ± 554	1303  ± 143	1907  ± 190	250  ± 25	344  ± 20	343  ± 18
+/+	15	6612  ± 924	1596  ± 147	1908  ± 232	211  ± 21	352  ± 35	369  ± 34

Monoamine content (nanograms per gram of wet weight of tissue) was measured by HPLC with electrochemical detection. Data are expressed as mean ± SEM. There were no significant differences among the three genotypes by ANOVA for each compound.