Table 1.
Treatment | Wild-type C57B1/6J | ApoE-KO | ||
---|---|---|---|---|
Weight (mg) | SE | Weight (mg) | SE | |
Control | 72 | 9 | 65 | 6 |
OVX | 20* | 2 | 18* | 2 |
OVX + E2 | 183* | 16 | 165** | 15 |
OVX caused a threefold decrease, and E2 replacement caused a 2.5-fold increase in uterine weight in both WT and apoE-KO mice. There were no significant strain or strain × treatment interaction effects.
*p < 0.0001.
**p < 0.01.