Fig. 5.

The Ca²⁺ channel blocker verapamil reduced the response of both neurons and astrocytes.A, Kinetics of the [Ca²⁺]_i change in one representative neuron (continuous line) and one astrocyte (dotted line) from the CA1 hippocampal region on K⁺ stimulation before and after slice perfusion with 100 μm verapamil. B, Mean relative decrease ± SE in the amplitude of the response to K⁺ stimulation from neurons (open bars labeled N1 and N2 report the amplitude of the first and second [Ca²⁺]_i peaks respectively;n = 33, 2 experiments) and astrocytes (A, stripped bars; n= 8, 2 experiments) after slice perfusion with 100 μmverapamil.