Properties of outward currents in type I neurons. In all experiments shown hereunder, currents were elicited by jumping the voltage from a −120 mV holding potential to 0 mV. Currents shown in records labeled 3 were obtained by subtraction of currents recorded after exposure to X-cAMP or 100 μm 4-AP (2) from control outward currents (1). A, top record, Maintained outward current abolished by cAMP analogs. Bottom record, Slowly inactivating cAMP-sensitive outward currents.Inset, Reversibility of effect of X-cAMP on outward currents in type I neurons. Reversibility was monitored 1–2 min after exposure to X-cAMP. B, Blockade by 100 μm4-AP of cAMP-sensitive currents in type I neurons.