Table 1.
Outward current properties in Drosophila larval neurons
| Neuron type | N | I peak (pA) | τ1(msec) | τ2(msec) | A1 | A2 | Blocker | Amplitude of cAMP-sensitive currents (pA) |
|---|---|---|---|---|---|---|---|---|
| Wild type | ||||||||
| I | 54 | 397.8 ± (43.4) | 162.3 ± (7.5) | 4-AP | 212.5 ± 47 | |||
| II | 74 | 499.3 ± (58.4) | 88.9 ± (2.7) | TEA | ||||
| III | 23 | 346.3 ± (57.7) | 7.2 ± (0.5) | 98.5 ± (9.3) | 0.78 ± (0.01) | 0.22 ± (0.01) | 4-AP (>10 mm) | |
| IV | 351 | 522.0 ± (21.1) | 14.2 ± (0.4) | 110.1 ± (2.6) | 0.46 ± (0.01) | 0.54 ± (0.01) | 4-AP, TEA | 150 ± 17 |
| dunce | ||||||||
| I | 3 | 859.7 ± (260) | 158.0 ± (8.8) | 4-AP | 562, 257 | |||
| II | 35 | 326.2 ± (43.0) | 87.9 ± (4.8) | TEA | ||||
| III | 55 | 315.6 ± (35.5) | 10.7 ± (0.9) | 131.4 ± (17.7) | 0.77 ± (0.01) | 0.23 ± (0.01) | 4-AP (>10 mm) | |
| IV | 174 | 473.2 ± (54.0) | 14.1 ± (0.7) | 119.8 ± (6.1) | 0.46 ± (0.02) | 0.54 ± (0.02) | 4-AP, TEA | 130 ± 19 |
Outward current properties in different neuron types.I peak, Peak currents measured directly from experimental records at V = 0 mV. τ values are time constants obtained by single- or double-exponential fitting to experimental data. In type I and type II neurons outward currents inactivated along a single exponential, and τ1 represents the time constant for current decay. In type II and IV neurons outward currents inactivated double exponentially. Here, τ1 and τ2 are time constants; A1 and A2, relative amplitudes of fast and slow components, respectively, derived from fitting. Numbers in parentheses are SEM.