Fig. 2.

Current-clamp recordings of the responses to depolarization pulses of physiologically different subpopulations of principal cells. A, The vast majority of principal cells responds to current injection (bottom traces) by firing a single action potential, followed by accommodation (top traces). B, Silent principal cells do not fire action potentials from resting membrane potential, even after a large depolarization. C, Some principal cells can fire multiple action potentials on depolarization. Calibration bars apply toA–C.