Fig. 4.

Metabotropic glutamate receptors are required for initiation of neuronal domains. A, Bath application of 1 mm (+)-MCPG dramatically reduced the number of neuronal domains (p < 0.01, Student’st test). B, Bath application of 1 mm (+)-MCPG does not affect the size of the neuronal domains that persist, indicating that metabotropic glutamate receptors are only involved in the initiation of neuronal domains.Numbers above bars indicate the number of slices (A) or number of neuronal domains (B). An asterisk indicates a significant difference (p ≤ 0.01; student’st-test).