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. 1998 Feb 1;18(3):923–931. doi: 10.1523/JNEUROSCI.18-03-00923.1998

Table 1.

l-Arginine reverses the protective effects of NOS inhibition

Treatment Motor neuron survival* (%) n
None 35  ± 4 8
BDNF 100  ± 4 8
l-NAME 80  ± 6 4
l-NAME + l-arginine 47  ± 3 4
l-NAME + d-arginine 79  ± 4 4
d-NAME 32  ± 6 4

*The percentage of motor neuron survival was determined 24 hr after plating, as indicated in Materials and Methods. The number of cells in BDNF-treated cultures at 24 hr was taken as 100%. Values are the mean ± SD of n determinations from at least two independent experiments. The concentrations were 100 pg/ml BDNF, 1 mml-NAME; 2 mml-arginine; 2 mmd-arginine; and 1 mmd-NAME.

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