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. 1998 Jun 1;18(11):4393–4402. doi: 10.1523/JNEUROSCI.18-11-04393.1998

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Copyright © 1998 Society for Neuroscience

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Fig. 4. — TH immunoreactivity in the LC and substantia nigra. A, TH immunoreactivity in the LC of a saline-injected withdrawing rat; B, TH immunoreactivity in the LC of a saporin-injected withdrawing rat; C, TH immunoreactivity in the substantia nigra of a saline-injected withdrawing rat; D, TH immunoreactivity in the substantia nigra of a saporin-injected withdrawing rat. Note the profound reduction of TH immunoreactivity (arrow) in the LC of the saporin-treated rat (B); by contrast TH immunoreactivity in the substantia nigra of the saporin-treated rat (D) was not changed. Scale bar, 250 μm.