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Number of animals in each treatment group in which the indicated withdrawal sign was present
| Treatment | Salivation | Ptosis | Diarrhea | Chewing | Chattering | Chromo |
|---|---|---|---|---|---|---|
| Saline, MN (n = 12) | 11 | 11 | 8 | 7 | 6 | 6 |
| Saporin, MN (n = 14) | 13 | 12 | 11 | 6 | 7 | 5 |
| Saline, PN (n = 4) | 0 | 0 | 0 | 0 | 0 | 0 |
| Saporin, PN (n = 4) | 0 | 0 | 0 | 0 | 0 | 0 |
MN, Morphine/naltrexone; PN, placebo/naltrexone; Chromo, chromodaccryorrhea.
