Fig. 4.
Microdialysis measurements of extracellular amino acid concentrations in the center of the ischemic zone showed large elevations in almost all amino acids. Two-way repeated measures ANOVA showed that elevations in l-Glu (F = 5.645; p = 0.04) and GABA (F = 7.422; p = 0.03) were significantly lower in nNOS mutant mice (•) compared with wild-type littermates (○). See Table2 for quantitative efflux parameters. *p < 0.05 via post hoc Fisher’s PLSD analyses.