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. 1998 Nov 15;18(22):9453–9470. doi: 10.1523/JNEUROSCI.18-22-09453.1998

Fig. 13.

Fig. 13.

Concentration–effect relations for morphine in rats with unilateral Ce lesions or unilateral Ce sham lesions (n = 6 per group). For these curves, the concentration of formalin injected into either theipsilateral (A) orcontralateral (B) hindpaw was varied, whereas the dose of morphine was held constant at 5 mg/kg. Rating scale nociceptive scores were averaged across the second phase of the formalin test for all rats. The mean second phase nociceptive score for systemic saline-treated control rats (either lesion or sham lesion) was used as Emin for calculation of percentage of maximum possible antinociceptive effect (%MPE; see Experiment 4, Materials and methods).