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Four other nAChR agonists enhance the frequency of spontaneous EPSCs. ACh (A),Nicotine (B), DMPP(C), and Cytisine(D) all showed similar effects on the spontaneous EPSCs. These responses were recorded in normal ACSF with TTX (0.5 μm) and bicuculline (10 μm), and the neuron was clamped at −50 mV.
