Table 2.

PN3 mRNA cellular distribution in rat DRG

Group	Cell size	Number of neurons	Number of neurons hybridized	% hybridized
Normal	Small and medium	1105	850	77
	Large	364	160	44
Neuropathic	Small and medium	455	337	74
	Large	224	87	39

A total of 16 sections from normal rats and 7 from neuropathic rats containing 1469 and 679 neurons, respectively, were examined for PN3 hybridization. Area of each neuron was measured by digital tracing. Neurons with area <1200 μm² were categorized as small and medium, and neurons with area >1200 μm² as large. For a cell to be considered hybridized, its grain density was required to be subjectively several times higher than background level. Only clear, nucleolated neurons were counted.