Fig. 5.

Effect of pargyline (PARG, 10 μm, top), an MAO inhibitor, and sulpiride (SULP, 2 μm, bottom), a D2 autoreceptor antagonist, on the effects of Ro4–1284 followed by AMPH in slices from wild-type mice. Stimulated DA release is measured by cyclic voltammetry as the peak height of DA elicited by single electrical pulses, and baseline overflow is measured as the average DA concentration change over a 5 min period between stimulations. PARG or SULP was added to the slice 10 min before the first measurements. Results are the mean ± SEM of at least four independent experiments.