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. 1998 Mar 15;18(6):1970–1978. doi: 10.1523/JNEUROSCI.18-06-01970.1998

Table 2.

Morphological analysis of sciatic nerve myelin sheaths

Genotype Age (months) Processes Pathology (%)
Wild type
 Animal 1 1 280 2.1
 Animal 2 8 214 3.3
 Animal 3 8 299 2.3
 Animal 4 8 348 2.9
 Animal 5 12 230 4.8
 Animal 6 12 198 3.0
Total 1569 3.1 ± 0.17
L-MAGtrun
 Animal 1 1 308 1.3
 Animal 2 1 305 2.6
 Animal 3 8 265 6.0
 Animal 4 8 184 4.4
 Animal 5 12 282 2.8
 Animal 6 16 289 3.5
 Animal 7 16 202 2.5
 Animal 8 16 321 3.7
 Animal 9 16 285 5.3
Total 2541 3.6 ± 0.14

Randomly selected sheaths of sciatic nerves 5 mm distal to the sciatic notch were analyzed for the presence of multiple wraps, lack of compaction, and redundant myelin as described in Table 1. Electron micrographs at 5000× were examined. Data are presented as mean ± SE and were analyzed using the Student t test. No significant difference was found.

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