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. 1998 Mar 15;18(6):2009–2016. doi: 10.1523/JNEUROSCI.18-06-02009.1998

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Copyright © 1998 Society for Neuroscience

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Fig. 5. — Effect of the D₁ receptor antagonist SCH23390 on GABA_A IPSCs evoked by minimal stimulation.A, Superimposed IPSCs in control (trace 1) and after application of SCH23390 (1 μm;SCH, 15 min; trace 2). The D₁antagonist strongly reduced the amplitude of the GABA_AIPSCs. Each trace represents the average of 10–15 traces.B, Time course of the change in the amplitude of IPSCs on application of the D₁ antagonist SCH23390 and after coapplication of SCH23390 with the D₁ agonist SKF38393 (3 μm; SCH+SKF). The D₁antagonist SCH23390 strongly reduced the IPSC amplitudes and completely blocked the facilitating effects of the D₁ agonist SKF38393. Each point represents the amplitude of an IPSC evoked by minimal stimulation at a repetition rate of 0.1 Hz.