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. 1998 Mar 15;18(6):2118–2128. doi: 10.1523/JNEUROSCI.18-06-02118.1998

Fig. 7.

Fig. 7.

BDNF induces differentiation of GABAergic neurons, whereas IGF-I-generated neurons are principally non-GABAergic.A, B, IGF-I generated a population of non-GABAergic neurons. The arrow illustrates a cell that is immunoreactive for β-tubulin (A), but not for GABA (B, arrowhead). C, Quantitative analysis of the GABAergic neurons present after differentiation by BDNF, IGF-I, or IGF-I plus insulin. The results reveal that BDNF generated only GABAergic neurons, whereas IGF-I-generated and IGF-I plus insulin-generated neurons were principally non-GABAergic. In all, 100–120 neurons were examined per condition and within each experiment (n = 3); **p < 0.01.