Fig. 4.

Increase of spontaneous IPSCs induced by an α-adrenergic agonist, FNE. A, Spontaneous IPSCs in a layer V pyramidal cell under control conditions (a) and in the presence of 50 μmFNE (b). FNE induced the burst of IPSCs in this cell. B, The amplitude and frequency of spontaneous IPSCs were increased by application of FNE in a solution containing CNQX/APV. The currents at the black bars (a) and(b) are shown in A. Each bin in the histogram represents the frequency (Hz) of the spontaneous IPSCs for 10 sec.