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. 1998 Sep 1;18(17):7008–7014. doi: 10.1523/JNEUROSCI.18-17-07008.1998

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Copyright © 1998 Society for Neuroscience

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Fig. 1. — Reduction of mechanical nociceptive threshold (hyperalgesia) produced by PGE₂ 15 min after injection (PGE2) (100 ng; n = 12),l-NMA (1 μg; n = 6) plus PGE₂ (l-NMA/PGE2) (n = 12; p < 0.05), PGE₂ 5 min after injection [PGE2(5′)] (n = 6), l-NMA 5 min after PGE₂ (PGE2/l-NMA5′post) (n = 6; p < 0.05),d-NMA (10 μg) plus PGE₂(d-NMA/PGE2) (n = 6), ODQ (1 μg) plus PGE₂ (ODQ/PGE2) (n = 6), and l-NMA(n = 6) on mechanical paw-withdrawal threshold in rats. In this and subsequent figures, *p < 0.05. Higher values indicate greater hyperalgesia. The data for one behavioral experimental group, PGE₂, is repeated in more than one figure for ease of comparison.