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Reduction of the paw-withdrawal threshold by the A2 adenosine agonist CGS21680 after injection (1 μg; n = 6), l-NMA plus CGS21680 (l-NMA/CGS) (n= 6; p < 0.05), 5HT1A agonist8-OH-DPAT after injection (1 μg; n= 6), and l-NMA plus 8-OH-DPAT (l-NMA/8-OH) (n = 6; p < 0.05) on mechanical paw-withdrawal threshold in rats.
