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. 1998 Oct 1;18(19):8056–8064. doi: 10.1523/JNEUROSCI.18-19-08056.1998

Fig. 5.

Fig. 5.

Effect of APV on the activity evoked in the ipsilateral digastric muscle by application of EAA receptor agonists to the TMJ region. Line plots illustrate the activity evoked in the ipsilateral digastric muscle by two applications (solid arrow) each of glutamate (2.5 μmol), NMDA (0.5 μmol), or AMPA (0.5 μmol) in three individual experiments. The first application contained only the indicated EAA receptor agonist, whereas in the second application both the EAA and APV (0.5 μmol;solid line) were applied together to the TMJ. Note that co-application of APV reduced the magnitude for glutamate- and NMDA-evoked digastric muscle responses without affecting AMPA-evoked digastric muscle responses, indicating that this dose of APV was selective for NMDA receptors.