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HAP1 labeling of large and small inclusions in the rat brain. Light micrographs showing HAP1 immunolabeling of inclusions in neurons from the cortex (A), striatum (B), preoptic area (C), and the septal region (D) are shown. In globus pallidus (E), brainstem neurons (F), and Purkinje cells (G), HAP1 immunoperoxidase labels organelles that are smaller and more numerous than stigmoid bodies and may primarily be mitochondria. Scale bar, 10 μm.
