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P14 sciatic nerve cross-sections. P0, MAG, and NCAM immunostaining of cross-sectioned sciatic nerves from heterozygous (A, C, E) and homozygous (B, D, F) 14-d-old mice is shown. Note that there are differences in each set of panels between the heterozygote and the homozygote. P14 homozygote has less P0 (A vs B) and less MAG (C vs D),but more NCAM (Evs F) than the P14 heterozygote.Arrows in B and D mark corresponding regions. Ten-micrometer cryostat sections; scale bar, 50 μm.
