Skip to main content
. 1998 Apr 1;18(7):2550–2559. doi: 10.1523/JNEUROSCI.18-07-02550.1998

Fig. 5.

Fig. 5.

Estradiol suppresses miniature IPSCs evoked by puff application of hyperosmotic medium near the recorded cell soma.A, Control cell responding to osmotic challenge with a typical barrage of miniature IPSCs. B, Estradiol-treated cell expresses only a small series of mIPSCs. C, Frequency histogram of the sizes of the mIPSCs (in picoamperes) recorded in six control cells (404 events counted in a subset of the data for each cell). D, Frequency histogram of the total mIPSCs evoked in six estradiol-treated cells (24 hr) (210 events counted in a subset of data for each cell). E, Cumulative histogram of all the events counted in C andD, illustrating that a large proportion of medium-sized mIPSCs are absent after estradiol treatment. Cells were recorded with a patch pipette containing CsCl, and the extracellular medium also contained TTX, DNQX, and 2-APV. Cells were held at resting membrane potential (−60 mV). Ct, Control; Est, estradiol.