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Acceleration of recovery from desensitization by the selective calcineurin antagonist CC complex. A, Membrane currents (b) and [Ca2+]i transients (a) simultaneously recorded from a cell patched with CC complex (20 nm)-containing pipette. Note fast recovery of test current amplitude after the conditioning pulse of nicotine. B, Data pooled from three cells indicate an increase in recovery rate in the presence of CC complex (upward triangle). *, ** = p < 0.04 and 0.05, respectively.
