Table 1.

Characteristics of inward current and [Ca²⁺]_i rise evoked by 2 sec pulse of nicotine are not affected by drugs regulating protein kinase/phosphatase activity

	Apeak(nA)	Aend/Apeak(%)	τ1 (msec)	τ2(msec)	[Ca2+]i decay (%)
Control (n = 10)	1.1  ± 0.2	8  ± 5	110  ± 20	660  ± 100	50  ± 9
PMA (n = 14)	1.2  ± 0.2	11  ± 2	90  ± 10	760  ± 140	44  ± 7
Staurosporine (n = 13)	0.9  ± 0.2	12  ± 1	140  ± 20	730  ± 100	40  ± 6
Forskolin (n = 4)	1.0  ± 0.2	12  ± 7	110  ± 30	620  ± 60	47  ± 9
Rp-cAMPS (n = 10)	0.8  ± 0.2	15  ± 4	80  ± 10	640  ± 120	54  ± 13
CC complex (n = 3)	1.1  ± 0.2	15  ± 5	100  ± 10	430  ± 80	58  ± 9
Calyculin A (n = 5)	1.3  ± 0.3	10  ± 7	90  ± 30	510  ± 50	47  ± 13

Note that A_peak,A_end/A_peak, τ₁, and τ₂ values (measured as indicated in Materials and Methods) as well as the rate of [Ca²⁺]_i clearance (measured as percentage of its decay from peak value 30 sec after the conditioning pulse of nicotine) were independent of the above treatments.