Fig. 1.

A–D, Photomicrographs showing immunocytochemical staining of AVP (A,B) and CRH (C, D) in representative frontal sections of the external zone of the median eminence (ZEME) of wild-type (A,C) and GR antisense transgenic (B,D) mice. ZIME, Internal zone of the median eminence; III, third ventricle. E, CRH and AVP stores in the external zone of the median eminence (ZEME) in TG (hatched bars) and WT mice (black bars). CRH and AVP immunoreactivity in the ZEME and ZIME was evaluated by quantitative immunocytochemistry. CRH and AVP are expressed as a percentage of the mean values found in WT mice (% CTRL). Data are expressed as mean and SEM (n = 6); *p < 0.05, TG versus WT.