Fig. 2.

Distribution of CRH and AVP neurons (A) and relative numbers of CRH immunoreactive neurons (B) in the PVN of transgenic (TG) and wild-type (WT) mice. A, Area containing vasopressin neurons (hatched fields) in frontal sections (50 μm apart) throughout the PVN of a TG (left panels) and a WT mouse (right panels). Note the absence of a clear separation of parvocellular CRH neurons and magnocellular AVP neurons.Dots indicate the positions of nucleated CRH immunoreactive neural profiles. B, Cumulative numbers of nucleated CRH immunoreactive neurons in the PVN of WT and TG mice. Data represent mean and SEM (n = 4–5); *p < 0.05, TG versus WT.