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. 1998 Aug 15;18(16):6378–6387. doi: 10.1523/JNEUROSCI.18-16-06378.1998

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Fig. 6. — GABA_A receptor activation arrestsin vitro migration. Migration induced by 1 μm CACA is inhibited by the activation of GABA_A receptors with a 10 μm concentration of the agonist muscimol (▤). Direct inhibition of GABA_Areceptors with a 10 μm concentration of the antagonist bicuculline (▥) results in a potentiation of migration to CACA. In the presence of a 10 μm concentration of both muscimol and bicuculline (▩), levels of CACA-induced migration are comparable to migration in the presence of bicuculline only. CACA-induced migration is inhibited in the presence of picrotoxin (▪), which blocks GABA_C receptors. Data represent the percentage of the control level of migration averaged from multiple trials (muscimol,n = 5; bicuculline, n = 5; picrotoxin, n = 5; muscimol plus bicuculline,n = 3). Error bars indicate SEM.