Fig. 4.

Effects of growth in the presence of kinase inhibitors on whole-cell capacitance, determined as described in the Results. Shown are data for LY294002(A1), wortmannin (A2),ML-9 (B),KN-62 (C), andcalphostin C (D); putative targets of these inhibitors are indicated in parentheses. Membrane area was reduced by all inhibitors except calphostin C. Data presented in Figures 4-6 are drawn from the same population of neurons, and for all three figures numbers of cells are:wortmannin, 10 control, 11 experimental;LY294002, 3 control, 5 experimental;ML-9, 13 control, 10 experimental;KN-62, 8 control, 8 experimental; andcalphostin C, 14 control, 17 experimental.