Skip to main content
. 1998 Aug 15;18(16):6241–6253. doi: 10.1523/JNEUROSCI.18-16-06241.1998

Fig. 7.

Fig. 7.

Free radical generation, assessed by Rh 123 fluorescence, is greatly increased in cystine-deprived preOLs but not in mature OLs. A, Low-power fluorescent photomicrograph showing numerous Rh 123 fluorescent preOLs after a 15 hr exposure to cystine-depleted medium. B, Laser confocal digitalized image showing the cytoplasmic distribution of Rh 123 fluorescence in preOLs after a 15 hr exposure to cystine-depleted medium.C, Quantitation of the relative intensity of Rh 123 fluorescence (see Materials and Methods) in preOLs and mature OLs. There was a 3.9-fold increase in Rh 123 fluorescence in preOLs after 15 hr of cystine deprivation (PreOL-) compared with control (PreOL+). Statistical comparisons were among relative fluorescence intensity in control preOLs, control mature OLs, or treated mature OLs relative to treated preOLs. There was no significant increase in Rh 123 fluorescence in control versus treated mature OLs. *p < 0.001.