Table 2.
Control | Neurotrophins | |
---|---|---|
Threshold (mV) | −29.40 ± 1.10 | −32.1 ± 1.16** |
Rise time (msec) | 1.73 ± 0.10 | 1.46 ± 0.07** |
Peak amp (mV) | 81.45 ± 6.50 | 94.01 ± 3.60** |
Decay time (msec) | 3.90 ± 0.61 | 2.68 ± 0.22** |
AP width (msec) | 5.63 ± 0.69 | 4.14 ± 0.19** |
AHP amp (mV) | 10.90 ± 1.45 | 10.03 ± 0.91 |
Action potentials elicited in response to a glutamate pulse were recorded under current-clamp mode from E16 hippocampal neurons cultured for 14 d in the presence or absence of BDNF plus NT-3. Data are presented as mean ± SEM of 12 control neurons or 13 neurotrophin-treated neurons. **p < 0.01 vs control values using Student’s t test. amp, Amplitude; AP, action potential; AHP, afterhyperpolarization.