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A, Potentiation of ATP response represented by P2X4+6 channel current phenotype at day 5.Arrows indicate beginnings of ATP applications (10 sec).B, Time course of heteromeric P2X4+6expression. Kinetics of appearance of functional ATP receptors on plasma membranes is strikingly different in oocytes coinjected with P2X4 and P2X6 subunits compared with those injected with P2X4 subunits (averages ± SEM from 3 to 15 oocytes in 2–8 independent experiments).
