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. 1998 Sep 15;18(18):7336–7350. doi: 10.1523/JNEUROSCI.18-18-07336.1998

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Copyright © 1998 Society for Neuroscience

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Fig. 8. — Immunoblot analysis of the synaptic proteins synaptotagmin I (SYNTG), synaptophysin (SYTPH), syntaxin 1 (SYTX1),SNAP-25, and of α-tubulin (TUB) intrkB (−/−) and trkC (−/−) mice and control littermates. Densitometric analysis (n = 2 animals per group, considering α-tubulin levels as reference) revealed decreases of 27% (SYNTG), 44% (SYTPH), 39% (SYTX1), and 46% (SNAP-25) in trkB (−/−) mice compared with control littermates. trkC (−/−) mice showed moderate reductions in SNAP-25 (24%) and synaptotagmin (22%), and slight reductions (7–5%) in synaptophysin and syntaxin 1.