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. 1998 Dec 1;18(23):9716–9726. doi: 10.1523/JNEUROSCI.18-23-09716.1998

Fig. 10.

Fig. 10.

Effect of N2O on GABAergic IACs.A, Left, The effect of N2O on the IAC in baseline conditions. Right, The effect of 25 μm pentobarbital (Pb) on IACs from the same neuron. After the experiment, 25 μm bicuculline (Bic) was added to confirm that the response was a GABAergic IAC. Average peak amplitude of 21 baseline IACs was −4029 ± 797 pA. B, Summary data showing the effect of 80% N2O (n = 21) and 25 μmPb (n = 4) on the 10–90% decay time of GABAR IACs. The average 10–90% decay time for 21 baseline IACs was 101.4 ± 18.1 msec. C, Paired-pulse stimulation of the GABAergic neuron depicted inA demonstrating that there is no change in paired-pulse depression in cells that show a prolonged IAC. Responses are superimposed IACs in the presence of air and N2O.