Fig. 5.
Effect of LyCEP on isolated CDC neurons.A, Effect of LyCEP on membrane potential. A representative intracellular recording of an isolated CDC at the resting membrane potential (−60 mV) to which 10 μm LyCEP (top) or vehicle (bottom) was applied under continuous superfusion. The horizontal lineindicates the moment and duration of application. B, Effect of LyCEP on spiking activity. A representative intracellular recording of an isolated CDC with spontaneous beating activity to which 5 μm LyCEP (top) or vehicle (bottom) was applied under continuous superfusion. Thehorizontal line indicates the moment and duration of application.