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Effect of LyCEP on an isolatedLymnaea auricle. A, Contractions of an auricle that was dissected from the heart and placed in a displacement chamber. At the indicated time (arrow), 1 μm LyCEP was applied directly onto the auricle under continuous superfusion. B, Dose–response curve of the increase in beat rate induced by synthetic LyCEP on the isolated auricle. Each data point is the mean of at least seven determinations. Error bars denote SEM.
