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. 1998 Dec 1;18(23):9910–9923. doi: 10.1523/JNEUROSCI.18-23-09910.1998

Fig. 5.

Fig. 5.

Timing and tempo of generation of corticospinal neurons. A, Developmental changes of the radial position of FG neurons born on E13.5, E15.5, and E16 with respect to corticospinal neurons. Small ×: retrogradely labeled CSNs; red dots, FG neurons; red stars, DLNs (i.e., corticospinal–FG neurons). B, C, Cumulative representation of the generation rate (DLN/CSN) where the cumulated number of DLN produced during the period of corticospinal neurons production divided by the total number of corticospinal neurons is taken as 100%. This measure provides a temporal description of corticospinal neuron production in normal (B) and reeler(C). D, E, Comparison of percentages of DLN/CSN in reeler and normal in area 6 (D) and area 3 (E). Statistical analysis: *p < 0.05, **p < 0.01, according to a χ2analysis. PS, Pial surface; WM, white matter/gray matter limit. Scale bar, 500 μm.